Interactive Data Portals provide a user-friendly way to access and explore our published and unpublished datasets.
We’ve created interactive platforms to share high-resolution datasets from our work on the placental barrier across evolution. These include single-nucleus RNA sequencing (snRNA-seq) data from the Jamaican fruit bat placenta, spatial and single-cell datasets from swine placentas, and snRNA-seq from human trophoblast organoids and human tissue. These portals allow you to visualize gene expression, explore cell types, and compare across conditions in an accessible, user-friendly format. Dive into the data and discover how the placenta defends and develops across species.
Explore the intricate cellular landscape of the Artibeus jamaicensis placenta through the advanced technique of single-nucleus RNA sequencing (RNA-seq). This interactive application allows users to effectively visualize gene expression patterns, identify various cell types, and compare trophoblast and immune cell populations across different developmental states. It serves as a unique and valuable resource for deepening our understanding of the remarkable placental adaptations that have evolved in bats.
Explore various single-nuclei sequencing datasets derived from human trophoblast organoids that have been cultured under different culture conditions. In this interactive portak, you can also compare these datasets to those obtained from both full-term and first trimester human placental tissue, allowing for a comprehensive understanding of cellular characteristics and behaviors in these distinct contexts.
This interactive portal prominently features both spatial transcriptomics and single-cell RNA sequencing (RNA-seq) data derived from the swine maternal–fetal interface, including detailed analyses of trophoblast organoids. Users are provided the opportunity to explore various cell types, intricate gene expression patterns, and the spatial organization of crucial placental regions. Additionally, the portal integrates a CellChat-based analysis, which allows users to visualize complex cell–cell communication networks, offering valuable insights into how different cells coordinate their functions to effectively support the processes of pregnancy. This innovative tool enables dynamic exploration of early-life immune and developmental biology in a large animal model that is physiologically relevant.